REGIME CHANGE GETS DOWN TO THE ISSUE OF VARIABLES AND PROBABILITY: There are a few rogue state regimes but there are a zillion ways for them to kill large numbers of people, often by misusing objects and substances with legitimate purposes ( see for example
Biological Weapons of Mass Destruction ). Rocket science is * not* required unless your aim is constructing a thermonuclear device small enough to fit into a cruise missile or car trunk; all that is needed to wreck immense amounts of havoc is the equivalent of a good High School level knowledge of physics and an undergraduate level education in microbiology. It is far easier to deal with a handful of regimes than to attempt to police all the goods and knowledge that could potentially cross their frontiers.